Spinach Artichoke Grilled Cheese

Featured in: Weeknight Dinners

This spinach artichoke grilled cheese elevates the comfort classic with a creamy, savory filling made from spinach, artichoke hearts, mozzarella, cream cheese, and Parmesan. Simply sauté fresh spinach, combine with artichokes and cheese ingredients, spread onto sourdough, and pan-fry until golden and melted. Ready in just 25 minutes, it serves two and pairs beautifully with tomato soup for a satisfying meal.

Updated on Sun, 18 Jan 2026 13:21:00 GMT
Crispy golden sourdough sandwiches stuffed with creamy spinach artichoke grilled cheese, served hot and melty. Pin It
Crispy golden sourdough sandwiches stuffed with creamy spinach artichoke grilled cheese, served hot and melty. | metroladle.com

My neighbor knocked on my door one afternoon holding a jar of artichoke hearts she didn't know what to do with. I had spinach wilting in the fridge and a craving for something warm and melty. We stood in my kitchen improvising, spreading cream cheese onto sourdough like we were finger painting. The smell of toasted bread and garlic filled the apartment, and she declared it better than any restaurant version she'd tried.

I started making these sandwiches on rainy Sundays when I wanted comfort food but also wanted to feel like I was taking care of myself. The combination of crispy sourdough and that warm, garlicky filling became my answer to gray skies. I've served them to friends who swore they didn't like artichokes, and they always asked for the recipe halfway through eating.

Ingredients

  • Shredded mozzarella cheese: This is the stretchy, melty backbone of the filling, and using pre-shredded saves time without sacrificing texture.
  • Cream cheese, softened: It binds everything together and adds a tangy richness that keeps the filling creamy instead of greasy.
  • Grated Parmesan cheese: A little goes a long way for sharp, nutty flavor that balances the mild mozzarella.
  • Unsalted butter, softened: Softened butter spreads evenly on the bread without tearing it, giving you that perfect golden crust.
  • Fresh spinach, chopped: Fresh wilts down quickly and tastes brighter than frozen, though frozen works if you squeeze out all the water.
  • Canned or jarred artichoke hearts, drained and chopped: Make sure to drain them well or the filling will be watery and the bread will get soggy.
  • Small garlic clove, minced: One clove is enough to give the filling a warm, aromatic backbone without overpowering the cheese.
  • Sourdough bread: The slight tang and sturdy texture hold up to the creamy filling and crisp beautifully in the pan.
  • Salt, black pepper, and red pepper flakes: Simple seasonings that brighten the filling and add a subtle kick if you want it.

Instructions

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Wilt the spinach:
Add the spinach to a medium skillet over medium heat with just a splash of water, stirring until it collapses and turns bright green. Drain it well in a sieve, pressing out the moisture so your filling doesn't turn soupy.
Mix the filling:
In a bowl, combine the wilted spinach, chopped artichokes, cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if using. Stir until everything is evenly blended and creamy.
Assemble the sandwiches:
Spread the spinach-artichoke mixture generously onto two slices of sourdough, then top with the remaining slices. Press down gently so the filling sticks to the bread.
Butter the bread:
Spread softened butter evenly on the outside of each sandwich, covering all the way to the edges. This ensures every bite has that crispy, golden crust.
Grill the sandwiches:
Heat a large nonstick skillet or griddle over medium heat and place the sandwiches in the pan. Cook for 3 to 4 minutes per side, pressing gently with a spatula, until the bread is deeply golden and the cheese inside is melted and gooey.
Serve:
Remove from heat, slice each sandwich in half, and serve immediately while the filling is still warm and stretchy.
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A close-up of spinach artichoke grilled cheese with melted mozzarella oozing from buttery toasted sourdough slices. Pin It
A close-up of spinach artichoke grilled cheese with melted mozzarella oozing from buttery toasted sourdough slices. | metroladle.com

The first time I made this for my sister, she paused mid-bite and said it tasted like the appetizer we used to split at our favorite restaurant, but better because it was warm all the way through. That's when I realized this sandwich had become more than just lunch. It was a way to bring a little luxury into an ordinary afternoon.

Choosing Your Bread

Sourdough is my favorite because the tangy flavor plays off the creamy filling and the crust gets incredibly crispy. I've also used whole wheat for a nuttier taste and multigrain for extra texture. Whatever you choose, make sure the slices are sturdy enough to hold the filling without falling apart when you flip them in the pan.

Making It Your Own

I sometimes stir in a handful of chopped fresh basil or a pinch of smoked paprika for a different flavor angle. A thin slice of tomato tucked into the filling adds juicy brightness, though it can make things a bit messy. If you like heat, a few dashes of hot sauce mixed into the filling gives it a nice kick without overwhelming the cheese.

Serving and Pairing Ideas

This sandwich begs to be dunked into a bowl of tomato soup, and I won't apologize for how good that combination is. A simple green salad with lemon vinaigrette balances the richness, or you can serve it with pickles and chips for a casual lunch. I've even cut them into small squares and served them as party appetizers, and they disappear fast.

  • Pair with tomato soup or a cup of creamy tomato bisque for dipping.
  • Serve alongside a crisp arugula salad dressed with lemon and olive oil.
  • Cut into quarters and serve as an appetizer at gatherings.
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Sliced halves of spinach artichoke grilled cheese reveal a rich, garlicky filling on a cozy lunch plate. Pin It
Sliced halves of spinach artichoke grilled cheese reveal a rich, garlicky filling on a cozy lunch plate. | metroladle.com

This sandwich has saved me on countless busy evenings when I wanted something satisfying without a lot of fuss. I hope it becomes one of those recipes you reach for when you need comfort, flavor, and a little bit of joy all at once.

Recipe FAQs

Can I prepare the filling in advance?

Yes, you can make the spinach-artichoke filling up to 24 hours ahead and store it in an airtight container in the refrigerator. Simply assemble and cook when ready to serve.

What bread works best for this sandwich?

Sourdough is ideal due to its sturdy crust and tangy flavor, but whole wheat, multigrain, or brioche are excellent alternatives. Choose bread thick enough to hold the filling without becoming soggy.

How do I prevent the bread from burning while the cheese melts?

Use medium heat rather than high, and don't rush the cooking process. Cover the skillet with a lid for the last minute to trap steam and ensure the cheese melts before the bread browns too much.

Can I add other vegetables to this filling?

Absolutely. Roasted red peppers, sun-dried tomatoes, caramelized onions, or fresh basil all complement the spinach and artichoke base beautifully.

Is this suitable for vegetarians?

Yes, this sandwich is completely vegetarian. All ingredients are meat-free, making it an excellent option for vegetarian diets.

What's the best way to serve this sandwich?

Serve immediately while the cheese is still warm and gooey. Pair it with tomato soup, a side salad, or pickles for a complete meal.

Spinach Artichoke Grilled Cheese

A gourmet twist on classic grilled cheese with creamy spinach and artichoke filling between crisp, golden sourdough slices.

Prep Time
15 minutes
Cook Duration
10 minutes
Total Duration
25 minutes


Skill Level Easy

Cuisine Type American

Output 2 Portions

Diet Details Meat-Free

What You Need

Dairy

01 1 cup shredded mozzarella cheese
02 1/2 cup cream cheese, softened
03 1/4 cup grated Parmesan cheese
04 2 tablespoons unsalted butter, softened

Vegetables

01 1 cup fresh spinach, chopped
02 1/2 cup canned or jarred artichoke hearts, drained and chopped
03 1 small garlic clove, minced

Bread

01 4 slices sourdough bread

Seasonings

01 1/4 teaspoon salt
02 1/8 teaspoon freshly ground black pepper
03 Pinch of red pepper flakes, optional

How To Make It

Step 01

Prepare the Spinach: In a medium skillet over medium heat, add spinach with a splash of water. Sauté for 1-2 minutes until wilted, then drain excess moisture.

Step 02

Combine Filling Ingredients: In a mixing bowl, combine sautéed spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if using. Mix until well blended.

Step 03

Assemble Sandwiches: Spread the spinach-artichoke mixture evenly onto two slices of sourdough bread. Top with the remaining bread slices to form two complete sandwiches.

Step 04

Butter the Exterior: Spread softened butter on the outside of each bread slice on both sandwiches.

Step 05

Cook the Sandwiches: Heat a large nonstick skillet or griddle over medium heat. Place sandwiches in the skillet and cook for 3-4 minutes per side, pressing gently, until bread is golden brown and cheese is melted.

Step 06

Finish and Serve: Remove from heat, slice each sandwich in half diagonally, and serve immediately.

Tools Needed

  • Medium skillet
  • Mixing bowl
  • Spatula
  • Large nonstick skillet or griddle
  • Knife

Allergy Advice

Review each item for allergens. If you're unsure, speak with a medical expert.
  • Contains milk from cheese and butter
  • Contains wheat from sourdough bread
  • May contain traces of soy or nuts depending on bread and cheese brands

Nutritional Info (per portion)

Treat these details as a guide—they're not a substitute for professional medical advice.
  • Energy: 430
  • Fats: 24 g
  • Carbohydrates: 39 g
  • Proteins: 16 g